Infektionen

Zusammenfassung

Zahlreiche Naturstoffgruppen besitzen experimentell nachgewiesene Wirkungen und greifen günstig und schonend in die Pathomechanismen von Infektionen ein. Durch die Beeinflussung der unspezifischen Abwehrreaktionen wie der mukoziliären Clearance, der Zilienschlagfrequenz, einer antiphlogistischen und lokalen antiseptischen Wirkung sind Phytopharmaka imstande, bei rechtzeitiger Gabe bakterielle Superinfektionen, aber auch schwere Komplikationen ohne Gabe von Antibiotika zu verhindern. Dies bedarf jedoch einer besonders sorgfältigen Nachkontrolle der Patienten. Die antimikrobielle Wirksamkeit beruht nicht nur auf einer direkten antiseptischen Wirkung auf Mikroorganismen, sondern auf der Blockierung eines wesentlichen Pathomechanismus von Keimen, nämlich der Adhärenz. Dass dieser Mechanismus auch zur Verhinderung einer Abstoßungsreaktion mit Halbierung der Todesfälle bei lebensbedrohlich kranken Patienten nach Knochenmarktransplantation führt, ist besonders bemerkenswert und gibt Hoffnung auf weitere Therapiemöglichkeiten, die mit natürlichen pflanzlichen Heilmitteln durch intensive Forschung auf molekularbiologischer Ebene noch zu erzielen sind.

Summary

Infection: Rationale for phytotherapy in paediatrics

Several experiments have revealed the considerable positive effect of a number of natural substances on the pathomechanisms of infections. The influence of phytopharmaceutical agents on the unspecific preventive reaction such as frequency of ciliary motion, mucociliary clearance, antiphlogistic and local antiseptic effects have been scientifically proven. The list includes the capability of preventing severe complications during the onset of bacterial superinfections, as well as the prevention of severe complications without the use of antibiotics. However, this requires the special and careful ex post personal control of the patient. The antimicrobial effect is not just related to the direct antiseptic effect on the microorganism, but on the blockage of the essential pathomechanism of germs, i.e. adherence. The mechanism also leads to the prevention of a rejection with the halving of death cases in bone marrow transplantation patients. This particularly offers important possibilities for further therapy with plant remedies through intensive research in molecular biology.

Schlüsselwörter

Infektion - Atemwege - viral - bakteriell - Superinfektion - Adhärenz - mukoziliäre Clearance - Phytopharmaka - Sekretolyse

Key words

Infection - respiratory tract - viral - bacterial - superinfection - adherence - herbal medicinal products - secretolytic

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